What is Spravato®?
Spravato® (esketamine) is a prescription nasal spray medication approved by the FDA for adults with treatment-resistant depression (TRD) and depressive symptoms with suicidal thoughts or behavior. Unlike traditional antidepressants that affect serotonin, Spravato works on glutamate receptors—offering a new approach for people who haven’t found relief with standard treatments.
Spravato is administered in a certified medical setting, where patients are supervised throughout the treatment process. While individual results may vary, many patients report experiencing improvement in symptoms within hours to days—much sooner than the weeks typically required for oral medications. As part of a broader treatment plan, Spravato offers new hope for those who’ve struggled to find lasting relief.









